Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis
Zhang M, Zhang Y, He J, Wang X, Wang Y, Li L, Tao L, Zhang M, Shen X. Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis. Chin Med. 2024 Nov 22;19(1):164. doi: 10.1186/s13020-024-01035-4.
小鼠
心血管疾病
2024
Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment
Luo Y, Zhang F, Zhu L, Ye J, Pan HY, Lu X, Fan X. Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment. Chin Med. 2025 Jan 25;20(1):14. doi: 10.1186/s13020-025-01060-x.
大鼠
心血管疾病
2025
Integrating bioinformatics and ferroptosis to reveal the protective mechanism of Astragaloside IV on chronic heart failure rats
Yuan H, Shi M, Wei J, Liu C, Wang Z, Li Y, Guo Z. Integrating bioinformatics and ferroptosis to reveal the protective mechanism of Astragaloside IV on chronic heart failure rats. Sci Rep. 2024 Sep 6;14(1):20787. doi: 10.1038/s41598-024-72011-z.
大鼠
心血管疾病
2024
Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation
Luo Y, Ye T, Tian H, Song H, Kan C, Han F, Hou N, Sun X, Zhang J. Empagliflozin alleviates obesity-related cardiac dysfunction via the activation of SIRT3-mediated autophagosome formation. Lipids Health Dis. 2024 Sep 27;23(1):308. doi: 10.1186/s12944-024-02293-9.
小鼠
心血管疾病
2024
Leptin drives glucose metabolism to promote cardiac protection via OPA1-mediated HDAC5 translocation and Glut4 transcription
Yang F, He Y, Zhao L, Huang J, Du F, Tian S, Zhang Y, Liu X, Chen B, Ge J, Jiang Z. Leptin drives glucose metabolism to promote cardiac protection via OPA1-mediated?HDAC5?translocation and Glut4 transcription. Funct Integr Genomics. 2025 Jan 29;25(1):28. doi: 10.1007/s10142-024-01515-8.
小鼠
心血管疾病
2025
The mechanism by which piR-000699 targets SLC39A14 regulates ferroptosis in aging myocardial ischemia/reperfusion injury
Chi H, Chai Y, Ma L, Wang Y, Wu Q, Wang L, Zhai J, Ma F, Tian Y, Qi N, Peng J, Fu Y, Yang X, Huang H, Ma S. The mechanism by which piR-000699 targets SLC39A14 regulates ferroptosis in aging myocardial ischemia/reperfusion injury. Acta Biochim Biophys Sin (Shanghai). 2024 Mar 4;56(9):1352-1364. doi: 10.3724/abbs.2024024.
大鼠
心血管疾病
2024